Betaine promotes cell differentiation of human osteoblasts in primary culture
نویسندگان
چکیده
منابع مشابه
Pellet culture model for human primary osteoblasts.
In vitro monolayer culture of human primary osteoblasts (hOBs) often shows unsatisfactory results for extracellular matrix deposition, maturation and calcification. Nevertheless, monolayer culture is still the method of choice for in vitro differentiation of primary osteoblasts. We believe that the delay in mature ECM production by the monolayer cultured osteoblasts is determined by their state...
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Although sulfuretin, the major flavonoid of Rhus verniciflua Stokes, has a variety of biological actions, its in vitro and in vivo effects on osteogenic potential remain poorly understood. The objective of the present study was to investigate the effects of sulfuretin on in vitro osteoblastic differentiation and the underlying signal pathway mechanisms in primary cultured osteoblasts and on in ...
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ژورنال
عنوان ژورنال: Journal of Translational Medicine
سال: 2017
ISSN: 1479-5876
DOI: 10.1186/s12967-017-1233-5